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........ published in NEWSLETTER # 49

CHROMOSOME SEGREGATION AND ANEUPLOIDY
by Dr. B.K. Vig, University of Nevada, Reno (U.S.A.)

This timely volume on `Chromosome Segregation and Aneuploidy' (NATO ASI SERIES H72) provides information on basic and applied aspects of how chromosomes malsegregate and how aneuploidy originates. Besides the basic aspects of most current research in the field, the book also deals with environmental mutagenesis.

The reader will find an updated version and use of the most recent techniques of molecular biology and chromosome phenomenology employed to study chromosome segregation and most updated state_of_the_art on how to determine whether environmental agents can cause aneuploidy. This book is the most recent on the topic of centromere, kinetochore and spindle mechanisms associated with genesis and aneuploidy.

The very special feature of the book is the compilation of most recent studies dealing with cytogenetic, genetic, molecular biology and biochemical aspects of chromosome segregation. It shows where we are and where we are going.

There is no other single volume which puts together relevant information on the topic under discussion like this one. Various aspects of chromosome movement during cell division and the components which affect it are dealt with in a wide variety of specialised journals. This is the only volume which brings together the entire field, creating a coherent picture of the problems.
Reference books: A40, A101, H61, H72

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